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Studies of the EPO gene led to the identification of a cis -acting hypoxia-response element (HRE) in its 3'-flanking region [52, 53, 67, 80, 81] and HIF-1 was identified through its hypoxia-inducible HRE-binding activity [56]

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assembled the first public database of exome sequencing, RNA-seq and SNP array data for cNF

Pathogenesis of Preeclampsia and therapeutic approaches targeting the placenta

In contrast, MPLA primarily signals through MyD88-dependent to establish innate immune memory (39), and notably upregulates mitochondrial antioxidant enzymes such as SOD2, HO-1

Independent domains To ferret out how the mitochondria does it, the researchers used a combination of biochemical studies, computational methods, and genetic screens to discover that SLC25A39 is both a sensor and a transporter at the same time, Birsoy explains