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Several preclinical studies have reported that MEM leads to a reduction in A brain levels or reduces amyloid plaque burden in preclinical mice models of AD, which contributes to memory improvement [43]

Therefore, an 8-day period post-injection was allowed for disease development

Because angiogenesis is a defining hallmark of tumor growth and metastatic progression, any therapeutic agent that enhances neovascularization could, in theory, facilitate tumor expansion and promote metastatic dissemination

(2025) 11:e42682

20b.2.2 Urinary riboflavin excretion Flavins are excreted in urine mainly in the form of riboflavin (6070% of all urinary flavins) or other metabolites, such as 7hydroxymethylriboflavin (7-hydroxyriboflavin) and lumiflavin (Chastain and McCormick, 1987)

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