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Well-designed clinical trials in humans are needed

They are not intended for human or animal consumption and are not pharmaceutical products, supplements, or therapeutic agents

Full press release online via this link: MAAIF Ugandas Post Press release: Ministry of Agriculture, Animal Industry and Fisheries (MAAIF) starts compensation of Project Affected Persons (PAPs) of the National Oil Palm Project (NOPP) in Sango Bay, Kyotera District

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This isn't because 1:1 is mechanistically optimal in some provable way it's because researchers studying combinations of these compounds chose 1:1 as the default and the literature accumulated around that choice