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While the protection of normal cells against radiation-induced cell death by ebselen has been attributed to its ability to detoxify cellular/mitochondrial ROS through the GPx mechanism, the molecular mechanism contributing to its radio-sensitization effect in cancer cells is still not fully understood

A study by Wang and colleagues, conducted in C57LB/6 male mice, randomly administered 25, 50 and 100 mg/kg/day of Apigenin (corresponding to low, moderate and high dose, respectively), for 9 months

The fixed brains were frozen in ice-cold isopentane with Tissue Tech O.T.C

[DOI] [PMC free article] [PubMed] [Google Scholar] 56.Vermeire S, Dreesen E, Papamichael K, Dubinsky MC

Hajat, 2010 )

Role of Mitochondrial Reverse Electron Transport in ROS Signaling: Potential Roles in Health and Disease