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This method has its pros and cons, while being helpful to measure cytokines potentially at a more localized level, these PBMCs can be affected by cryopreservation, length of storage, and the overall processing methods

Skinner et al., 2019

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Despite the fact that only 510% of asthmatic patients do not respond to steroids, this leads to a significant socioeconomic burden and affects their quality of life as a result of the side effects associated with the prolonged usage of high doses of steroids

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