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Degradation tests were conducted by incubating the freshly prepared core-shell microspheres in a 96-well plate transferred using a micropipette

ISO is a typical inducer of cardiac fibrosis and its profibrotic mechanism is intimately linked to the generation of ROS and activation of c-Jun N-terminal kinase (JNK), p38 mitogen-activated protein kinase (MAPK) and extracellular signal-regulated kinase (ERK) (51,52)

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Subsequently, a SEM was employed to analyze the microstructural characteristics

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