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While all of the CYP enzymes discussed are involved in statin metabolism, it is likely that genetic variations in enzymes with major metabolism roles have a significant effect on statin disposition

Biochim Biophys Acta 1780:638651 Saito K, Kobayashi M, Gong Z, Tanaka Y, Yamazaki M (1999) Direct evidence for anthocyanidin synthase as a 2-oxoglutarate-dependent oxygenase: molecular cloning and functional expression of cDNA from a red forma of Perillafrutescens

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