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Conclusion: Contrary to popular belief, endometriosis is not a problem with reproductive organs

Ziegelhoffer, E

& Chang, E

Ovarian histology (follicle counts, fibrosis) and biochemical parameters (hormones, inflammatory and oxidative markers) were assessed

The primary resistance mechanisms include mutations in FCY2 , encoding cytosine permease (which mediates drug uptake), and mutations in FCY1 , encoding cytosine deaminase (required for 5-FC activation) (Longley et al., 2003