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Cel Biol 147, 14431456

Lung infection by Pseudomonas aeruginosa induces neuroinflammation and blood-brain barrier dysfunction in mice

This observation was especially significant with chloroquine treatment as monotherapy and the combination of sertraline and chloroquine in 1919 PSPH amp and PSPH V116I cell models, leading to a disrupted mitochondrial morphology, which appeared swollen and fragmented compared to healthy mitochondria (Fig