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Rupa B, Partha P, Amulya P, Pradip K, Ganesh G, Idan G et al

Furthermore, ncRNAs can also trigger the transcription of metabolic enzymes in a direct or indirect manner

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By selectively disrupting key antioxidant systemssuch as inhibiting glutathione synthesis with buthionine sulfoximine (BSO), blocking thioredoxin reductase with auranofin, or directly targeting NRF2therapies can push cancer cells beyond their limited oxidative buffering capacity