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Description

To identify the specific mechanisms by which cystine affects bacterial cells, we measured the GSH/GSSG ratios, intracellular ferrous iron concentrations, and ROS levels in bacteria cultured with exogenous cystine

Annunziata Lapolla, Maria Grazia Dalfr Expert Review of Endocrinology & Metabolism .2026

In 1957, Linus Pauling estimated the misactivation rate about 1 in 200 from a theoretical standpoint (Pauling 1958), although later experiments by Loftfield (Loftfield and Vanderjagt 1972) showed the in vivo misincorporation rate to be closer to 1 in 3000