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SEMA7A variants in animal models reduce the levels of canalicular membrane BAs transporters, like BSEP, in hepatocytes [11, 42]

Though FC and IBS-C both show familial tendency, genetic/epigenetic variants (e.g., SNPs in pain-related genes, microRNA dysregulation) and stress-induced corticotropin release further heighten susceptibility, particularly in IBS-C

Cortical Gamma-Aminobutyric Acid and Glutamate in Posttraumatic Stress Disorder and Their Relationships to Self-Reported Sleep Quality. Sleep, vol

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However, the increased ratio of exhausted T cells could be reversed by following anti-VEGF plus anti-PD-L1 treatment [73]

The nuclear SUMO-targeted ubiquitin quality control network regulates the dynamics of cytoplasmic stress granules