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Description

The rats had ad libitum access to standard chow and water

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Although pH values lower than 6.5 exhibit increased SGE formation in UGT74F2, they have no effect on SGE formation by UGT74F1 and, vice versa, at pH values higher than 6.5 SAG formation by UGT74F1 increases but is unchanged in UGT74F2

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The sticky, tar-like consistency makes adulteration more difficult compared to powders [11]

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Discussion To identify emerging senolytics, we screened a library of electrophilic compounds, which can target proteins through covalent bond formation

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The metabolism of alcohol by ADH and CYP2E1 leads to increased acetaldehyde and ROS formation

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