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Although experimental studies suggest potential pancreatic harm from GLP-1 RAs, robust clinical evidence demonstrates that these drugs do not increase the incidence of pancreatitis or pancreatic cancer in diverse human populations

Therefore, exogenous GSH exerted significant cerebral protective effects in AHE rats

Quantitative Recording of Rotational Behavior in Rats After 6-Hydroxy-Dopamine Lesions of the Nigrostriatal Dopamine System

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For instance, depletion of mGSH results in Trx2 oxidation (Zhang et al., 2007), while hypercholesterolemic pigs with selective depletion of mGSH in heart mitochondria, exhibit decreased levels of the mitochondria-specific antioxidant enzymes such as SOD2, Trx2, and Prx3 (McCommis et al., 2011)