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Furthermore, it is important to consider that molecular mechanisms that lead to reduced inflammation and lower oxidative stress may change with longer durations of the diet, and the reported short-term mechanisms of neuroprotection may not necessarily contribute to its long-term effects

Remaining missing values were imputed using gamma regression fit of the mean-variance trend with the single_imputation function from the PaiR library (github.com/PhilipBerg/pair)

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Li R, Li Y, Song Z, Gu Y, Jiao X, Wan C, et al

Bnip3 functions as a mitochondrial sensor of oxidative stress during myocardial ischemia and reperfusion

Lee, Molecular and Cellular Biology, DOI: 10.1158/1538-7445.AM2020-1239 Published August 2020