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The primary source of sulfur for pheomelanin synthesis is L-cysteine, making it an essential component of this process

It is important not to exceed the recommended dosage, as fat-soluble vitamins are stored in the body

Additionally, the development of pharmacological agents that precisely modulate intracellular iron homeostasis, such as iron chelators or iron oxide NPs, or enhance iron bioavailability specifically within the TME, may facilitate the targeted exploitation of ferroptosis pathways

Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes

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Luckily, reported anecdotes include minor side effects, like bloating and nausea