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Moran TH, Baldessarini AR, Salorio CF, Lowery T, Schwartz GJ

Research in animal models indicates that elevated NNMT expression is associated with reduced levels of the glucose transporter GLUT4

Folate supplements Active: Levomefolate (5-methyltetrahydrofolate) is the active, natural form of folate

Individuals with known hypersensitivity to ascorbic acid, those with a history of oxalate kidney stones, G6PD deficiency, iron overload disorders, or severe renal impairment should avoid this product

An implication of this is that lactic acid is an immuno-modulatory molecule that can strongly repress anti-tumor immunity

Students designing follow-on experiments often start with these signaling maps to frame their hypotheses