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Another possible reason may be that almost all enrolled patients with attenuated or disrupted RPE were extrafoveal and did not invade the fovea

7 Interactions between the cGAS-STING axis and ER stress during viral infection 7.1 The ER stress responses have important influences on viral survival There is adequate evidence that the state of the endoplasmic reticulum also influences a variety of selective autophagy, including mitophagy and ER-phagy (119, 120)

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As a consequence, the formation of peroxynitrite and reactive oxygen species (ROS) occurs 9,10

NPJ Breast Cancer 5 , 45 (2019)