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Some probiotics and fiber interventions may shift the microbiota to reduce TMAO formation, though more evidence is needed [6,13]

GCR/SlTOE/TPL2 complex suppress GCR1/2 expression To further dissect the relationship between GCR and SlTOE, we crossed pMTR1: GCR1-GFP and pMTR1:rSlTOE1B-GFP , and the result showed that the expression of pMTR1: GCR1-GFP repressed the gland formation induced by pMTR1: rSlTOE1B-GFP , indicating that GCR1 is genetically epistatic to SlTOE1B (Fig