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Research has shown that the levels of antioxidant defenses, as assessed through activities of SOD, catalase, and glutathione peroxidase, are naturally minimal within the colon and are primarily limited to the epithelial cells (85)

Unfortunately, this enzyme is also produced at elevated levels by pathogenic bacteria (i.e., E

Within the H-site, the substrate analogue ( 12 ) interacts through hydrogen bonds to N108 and the backbone of V12, a interaction with F112, water bridges to R16 and Y175, and hydrophobic interactions with V12 and V115 (Fig

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Healing of scar