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By influencing S-adenosylmethionine (SAM) levels, it also plays a role in epigenetic regulation and longevity-related gene expression, linking energy metabolism with cellular lifespan

Evid Based Complement Alternat Med 2020(1):6845383 Jiao C, Chen W, Tan X, Liang H, Li J, Yun H, Yang BB (2020) Ganoderma lucidum spore oil induces apoptosis of breast cancer cells in vitro and in vivo by activating caspase-3 and caspase-9

200 Enzyme-catalyzed reactions that generate ROS include those involving NADPH oxidase, xanthine oxidase, uncoupled endothelial nitric oxide synthase (eNOS), arachidonic acid and metabolic enzymes such as the cytochrome P450 enzymes, lipoxygenase and cyclooxygenase

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This reduces both extracellular free radicals and peroxides to water before damaging cells