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Description

These mutations result in decreased lysosomal function, impairing the processing of -Syn and leading to lipid accumulation and subsequent neurodegeneration

Allen, T

and Yang, S

It's an exciting challenge to gain insight this complexity because it will offer a great opportunity to design new drugs that will be able to target a particular pharmacological effect with limited side effects

References 1 BoltonVNHaydenCRobinsonMAbdoDPericleous-SmithA

They are pathway-level traits, not predictions: the genetic test never forecasts response to any specific compound, and it is not a drug-response predictor