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Neurodegeneration: Mller cells in the DR also exhibited ferroptosis features, including downregulation of SLC7A11, GSH, and GPX4 and upregulation of ACSL4 and MDA, leading to glutamate excitotoxicity (97)

Biochemical data for each metabolite were then normalized to the protein concentration as measured by Bradford assay to account for differences in metabolite levels due to differences in the amount of material present in each sample

Standard capsules often have an absorption rate as low as 10% or less because the molecule is so fragile

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(5) cytochrome P450 enzymes, a group of heme monooxygenases, which catalyse the metabolism of endogenous and exogenous molecules by electron transfer through NADPH cofactor, and finally (6) endoplasmic reticulum, which generates ROS in response to misfolded proteins (De Almeida et al