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In urethane-anesthetized female Wistar rats, L-theanine could reduce substance P-induced bladder hyperfunction through inhibiting pro-inflammatory protein kinase C (PKC)/ERK/NF-B/intercellular adhesion molecule 1 (ICAM-1)/IL-33 signaling, oxidative stress, apoptosis, autophagy (99)

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Qin X, et al

Inherent and benzo[a]pyrene-induced differential aryl hydrocarbon receptor signaling greatly affects life span, atherosclerosis, cardiac gene expression, and body and heart growth in mice

Concurrently, the NF-B signaling pathway is repressed, ultimately resulting in breast cancer cells (98)