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* Correspondence: Monica Barne, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Although these caspases do not directly activate IL-1 and IL-18, they can induce potassium efflux through non-selective pores on the membrane, thereby activating the NLRP3 inflammasome and up-regulating caspase-1, which indirectly activates the classical regulatory pathway of pyroptosis [112, 113]

It also contributes to good liver function.

Finally, in a cohort of female hospital workers, rapid rotating NS was linked to increased serum release of stress-related steroids-corticosterone, 11-deoxycortisol, DHEA, and androstenedione, whereas estradiol levels were slightly decreased, and salivary estradiol remained unchanged, suggesting a complex and multifaceted influence of NSW on estrogen regulation 188

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Zesiewicz TA, Hauser RA, Freeman A, Sullivan KL, Miller AM, Halim T