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Moreover, in B cells, glutamine deprivation-induced inhibition of mTOR activation can promote GSK3 inhibition and suppress IL-10 secretion [161]

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ABI Acute Brain Injury AD Alzheimers Disease ALS Amyotrophic Lateral Sclerosis APP Amyloid Precursor Protein A -Amyloid Protein DAMPs Damage-Associated Molecular Patterns DFO Deferoxamine D-PUFA Deuterated Polyunsaturated Fatty Acids GCLC Glutamate-Cysteine Ligase Catalytic Subunit GCLM Glutamate-Cysteine Ligase Modifier Subunit HD Huntingtons disease FPN Ferroportin Ft Ferritin GPX4 Glutathione Peroxidase 4 GSH Glutathione 4-HNE 4-Hydroxynonenal IREs Iron-Response Elements IRPs Iron-Regulatory Proteins LOOH Lipid Peroxides LRRK2 Leucine-Rich Repeat Kinase 2 MDA Malondialdehyde MECs Microvascular Endothelial Cells mtDNA mitochondrial DNA mHTT mutant huntingtin MS Multiple Sclerosis NAC N-Acetylcysteine NADPH Nicotinamide Adenine Dinucleotide Phosphate NCOA4 Nuclear Receptor Coactivator 4 NFT Neurofibrillary Tangles NRF2 Nuclear Factor Erythroid 2-Related Factor 2 PD Parkinsons Disease PUFA Polyunsaturated Fatty Acid ROS Reactive Oxygen Species RTAs Radical Scavengers SAH Subarachnoid Hemorrhage SCI Spinal Cord Injury System XC cystine-glutamate antiporter SLE Systemic Lupus Erythematosus SOD1 Superoxide Dismutase 1 TBI Traumatic Brain Injury TF Transferrin TfR Transferrin Receptor VD Vascular Dementia Glossary References 1 Alkhazaali-AliZ.Sahab-NegahS.BoroumandA