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CHOIR: A randomized, prospective trial, 1432 patients with anemia due to CKD who were not undergoing dialysis and who had not previously received epoetin alfa therapy were randomized to epoetin alfa treatment targeting a maintenance hemoglobin concentration of either 13.5 g/dL or 11.3 g/dL

255 Two clinical trials from the early 1990s reported fibromyalgia patients benefited from 5-HTP supplementation

KD has a documented impact on gut microbial composition and function, suggesting it may exert beneficial effects in PD through the gutbrain axis [169]

C.AvezumA.et al

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After a year and a half, the patients skin lesions gradually healed, only leaving scars (Figures 1DF)