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Nicotine in Diseases of Nervous System While neurodegenerative diseases appeared to be more prevalent in smokers than non-smokers, epidemiological studies during the early 1960s provide the first evidence of more smoking is used, less incidence of Parkinsons disease is observed [191, 192]

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However, some individuals may experience mild effects such as fatigue, nausea, or dizziness

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This exposes participants to cotinine (the main metabolite of nicotine found in the bloodstream) levels suggestive of moderate tobacco exposure, equivalent to that found in light/moderate cigarette smokers, the study notes

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