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Cytosolic or extracellular mtDNA induces an innate immune response, which triggers neuroinflammation via immune sensors like the cyclic GMPAMP synthase (cGAS)-stimulator of interferon genes (STING) pathway and Toll-like receptors (TLR) [11, 12]

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al., reported that IIb 3 (GPIIb/IIIa) integrin protein is activated by P2Y 1 -stimulated Ca 2+ signaling and P2Y 12 -stimulated activation of the PI3K kinase, which is essential for fibrinogen binding to the platelet of primary rat megakaryocytes(70)

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Evidence: Some studies have shown that omega-3 supplementation helps reduce insulin resistance markers, although effects on blood glucose levels are less pronounced

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