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The 3R allele for this variant is associated with a 24 fold increase in expression of the TYMS enzyme, as a result of the effect of this variant on the translation efficiency of TYMS

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120 These advanced technologies have mapped the precise spatial zonation of immune responses, revealing how distinct subpopulations of hepatic non-parenchymal cells, such as specific lipid-associated macrophages localized at fibrotic zones or bile ducts, uniquely respond to gut-derived metabolic signals

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