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Its very important to have placebo-controlled studies like this one, Paul Wang, Autism Speaks' senior vice president for medical research and pediatrician, said

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Vitamin B12 shots are an effective way to combat fatigue, support immune function, improve mental clarity, and promote healthy skin, hair, and nails

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Symptoms of B12 deficiency include: Low energy and fatigue Digestive problems Depression and moodiness Insomnia Brain fog and memory loss Anemia Reduced immune system function Tingling or numbness in the extremities Swollen tongue Loss of vision or hearing Jaundice Kidney disease Pale skin Poor circulation in the extremities If you are over age 50 and are experiencing one or more of the above symptoms, boosting your intake of B12 cannot hurt, and it may provide a safe and inexpensive solution while preventing a wrong diagnosis