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This increased binding may well be attributed to an increased surface area of the microspheres compared to homogenates, but further experiments would be needed to test this hypothesis

By inhibiting NNMT, 5-Amino-1MQ prevents this NAD drain , allowing cells to maintain higher NAD availability

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The novel anti-cancer fluoropyrimidine NUC-3373 is a potent inhibitor of thymidylate synthase and an effective DNA-damaging agent