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However, this process depends on several cofactors, including vitamin C, iron, and B vitamins

Although numerous studies have documented the therapeutic potential of SE for various diseases, to the best of our knowledge, we are the first to investigate the anti-neuroinflammatory and anti-amnesic effects of desalted and enzyme-digested SE ethanol extract (SE-EE)

For example, gene therapy has been used to reduce P-gp expression at the BBB, and RNA interference (RNAi) technology has been employed to silence the P-gp gene [86]

CCND1 cDNAs were subsequently transferred into pINDUCER20 (Addgene

Iron loading is a prominent feature of activated microglia in alzheimers disease patients

Details for carnitine measurements, physical activity experiments and respirometry experiments are described in the Supplemental Methods