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Gyurszov M, Gureck R, Bbkov J, Tthov

Additionally, the mutant huntingtin protein can impair the function of the transcription factor PGC-1, which is crucial for the regulation of antioxidant defenses and mitochondrial biogenesis

10.1172/JCI39492 20 HerzigS.ShawR

3 In a study using the rd1 mouse RP model, a mixture of antioxidants including alpha-tocopherol, ascorbic acid, Mn(III)tetrakis(4-benzoic acid)porphyrin and alpha-lipoic acid improved biomarkers of oxidative stress (protein carbonyl adducts and acrolein staining) and partially preserved cone function

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