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To rule out a possible toxic effect on the NuAc of the BSO dose used, we performed an activated caspase 3 (a marker of the execution-phase of cellular apoptosis) and neuroN (a marker of mature neurons) staining assay on accumbal sections from a subset of animals tested in the PR test (Supplementary Figure 3 i-l)

doi: 10.1210/mend.14.4.0438 38 TurnerJDMullerCP

The formation of 8-oxoG is the most common lesion in the DNA molecule

Although advances in optical diagnostic technology should reduce invasive testing for UTUC, urinary cytology remains a primary methods for screening and monitoring urothelial carcinoma (40,41)