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In: Higgins JPT, Green S (editors)

Special Dosing Situations for Severe B12 Deficiency In cases of severe Vitamin B12 deficiency, special dosing is key for treatment

Once weekly administration of this pharmaceutical agent, for 4 weeks, in diet-induced obesity in mice, resulted in improvement of obesity, hepatic steatosis, glucose control, and lipid profile

Oral supplements have not worked for you, which is common when an absorption problem is the underlying cause

Also, anyone following a vegan diet is more at risk as B12 is mainly found in animal sources of food

Researchers use half-life data to understand dosing frequency, expected duration of biological activity, and clearance kinetics