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Take Action Check List IF YOU DEVELOP ANY OF THE FOLLOWING SIGNS OR SYMPTOMS YOU MUST VISIT YOUR GP OR DERMATOLOGIST FOR IMMEDIATE CLINICAL ASSESSMENT: Seek immediate advice from your GP or dermatologist if a new or existing skin, nail or mucosal (lips, inside the mouth and nose and genitalia) pigmented or non-pigmented spot, lump, lesion, mole or freckle: Gets bigger and/or changes in shape, particularly getting an irregular outline

Studies have shown that elevated PAR levels are linked to hyperglycemia and subsequent oxidative stress in various tissues and cells of diabetic individuals (2628)