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Dissection of complex protein dynamics in human thioredoxin

Calculating the overall loading value: We determine the number of weeks per digit by multiplying the percentage loss of use per digit by the maximum allowable weeks per digit

doi:10.1210/me.2008-0201

The successful development of the first highly selective SQOR inhibitors demonstrates that SQOR is indeed a druggable target, opening a new paradigm for treating diseases like heart failure ( in vivo monitoring methods for H 2 S and its metabolites to stratify patients and monitor treatment responses before advancing SQOR-targeted therapies

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