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doi: 10.1038/s42003-020-01172-0 203 YoshimuraK.MasudaA.KuwanoM.YokotaA.AkashiK

Furthermore, in patients with HCV-related chronic liver disease, levels of taurine-conjugated BAs strongly correlated with increased hepatic S1PR2 expression, markers of inflammation (NLRP3 inflammasome, NF-B pathway genes), and liver disease severity, suggesting a pathological role for the Tau-BA-S1PR2 axis in hepatic inflammation (104)

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and 2 types of small molecular Hyaluronic Acid (PrimalHyal 50, Hyalo-Oligo) Rich with Hyaluronic Acid activating factor EXO-H that stimulates the bodys own secretion of hyaluronic acid to boost hydration, it is recommended to drink a glass of water after completing the skincare procedure for increased synergistic effect of the advanced self-hydrating mechanism