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In a study in almost 84 000 postmenopausal women, intake of fiber, fruits, and vegetables were each associated with lower risk of first-time kidney stone episodes

In addition to the impairment of the antioxidant enzyme system, the non-enzymatic antioxidant defense system may also be affected

Furthermore, ROS-induced stimulation of ion channels and correlated K + deficit cause cell shrinkage and reduced viability, caspase-like activity as well as PCD [138]