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Ammonia and carnitine concentrations in children treated with sodium valproate compared with other anticonvulsant drugs

Despite a plethora of studies examining the effects of GSNO both in vitro and in vivo , few studies have identified the compound which actually S-nitrosates a specific protein thiol, whether it be GSNO or another GSNO-derived low molecular weight S-nitrosothiol (e.g., L-CysNO)

The reduction in antioxidant expression can be linked to the age-related decline in Nrf2/ARE activity (Zhang et al., 2015)

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10.1152/ajpgi.00322.2010 Am

A similar effect is achieved by increasing the insulin receptor sensitivity, which may be the basis for treating insulin resistance because, this way, a larger amount of glucose could enter the cells and be converted into energy