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Nature 509, 96100

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Liver inflammation is characterized by the invasion of inflammatory cells that produce cytokines, including IL-6 and TNF-, and is caused by many aggravators, such as many drugs, alcohol consumption, viruses, pregnancy complications, and some metabolic diseases

Neurobiol Aging 107:128141 [DOI] [PubMed] [Google Scholar] 87.Cardo LF, Monzn-Sandoval J, Li Z, Webber C, Li M (2023) Single-cell transcriptomics and in vitro lineage tracing reveals differential susceptibility of human iPSC-derived midbrain dopaminergic neurons in a cellular model of Parkinsons disease

Binding of the substrate(s) in the substrate binding pocket and ATP hydrolysis in the NBDs induce a conformational change and move the substrate from high-affinity to low-affinity binding, from where the substrate is released into the surrounding space, facilitated by ATP hydrolysis or by the law of mass action, and the transporter returns to its pre-transport state

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