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The homocysteine-inducible, endoplasmic reticulum (ER) stress-inducible, ubiquitin-like domain member 2 (HERPUD1) in cultured HELA cells facilitate cytoprotective effects against oxidative stress by suppressing the inositol 1,4,5-triphosphate receptor and reducing the transfer of calcium ions from the endoplasmic reticulum to mitochondria [41]

Add 80 l 10 mM HCl, and lyse the cells by freezing and thawing twice

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Free radicals are unstable molecules that can originate from environmental factors like pollution and toxins, as well as natural processes such as metabolism

Structures of compounds discussed in this section are shown in Figure 9A