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Complicating matters: While there are genes (such as GSTM1) that produce enzymes that facilitate the creation and recycling of GSH throughout the body, these genes are impaired in some people

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Similarly, acetaminophen overdose leads to the formation of a toxic metabolite, N-acetyl-p-benzoquinone imine (NAPQI), which depletes glutathione and induces oxidative stress in the liver [57]

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