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2016 Feb;55(1):207-17

Results from the LMER models with the same effect size direction in the discovery and replication cohorts were then meta-analysed using fixed-effects meta-analysis implemented via the R package metafor (v.4.40)

Supplementary Table 1

Following successful amplification by monoplex PCR, two distinct pools containing the 21 optimized primer pairs were used for multiplex PCR, maintaining a final primer concentration of 0.1M

At the initial baseline visit, serial venous sampling performed after oral d 3 -l-carnitine challenge revealed rapid increases in plasma concentrations of d 3 -l-carnitine, and subsequent increases in d 3 -BB and d 3 -TMAO following a lag phase (Figure 1, AC, filled circles)