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In PEM, there are insufficient building blocks and energy to make immune cells and immune factors that protect the body from infection and disease

Plant Physiol 94:13901401 Srivalli S, Khanna-Chopra R (2008) Role of glutathione in abiotic stress tolerance

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This microenvironment further deteriorates during the degeneration process, not only severely affecting the survival and function of resident cells but also posing severe challenges for stem cell transplantation therapy