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Similar content being viewed by others Introduction Crohns disease (CD), a form of inflammatory bowel disease (IBD), is characterized by inflammation and ulceration in the gastrointestinal tract

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Dissection microscopy, H&E staining (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 134.Berhane K., Widersten M., Engstrm A., Kozarich J.W., Mannervik B

We found that the cells form the TARDBP family have an impaired defense system against oxidative stress, with lower glutathione levels respect to the unrelated CTRLs, suggesting reduced abilities to cope with oxidative stress, which may account for the increase in ROS levels, despite the upregulation of SOD2 expression in patients cells

SIRT5 functions as a global regulator of mitochondrial lysine succinylation and involved in metabolic regulation [124]