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Genome-wide DNA methylation profiling identifies epigenetic signatures of gastric cardiac intestinal metaplasia

As hemoglobin breaks down and energy is harvested through the intricate mitochondrial respiratory pathway, GSH meticulously creates a reducing environment, akin to a fortress against oxidative damage

Exp Toxicol Pathol 44: 273281

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Mol Brain (2020) 13:125

[3] Hyperpigmentation in B12 deficiency occurs as a result of (1) decreased levels of reduced glutathione which activates tyrosinase and results in increased melanin synthesis, (2) defect in transfer of melanin from melanocytes to keratinocytes resulting in pigment incontinence, (3) increased biopterin in B12 deficiency increases hydroxylated phenylalanine which results in hyperpigmentation