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To address this, providers sometimes recommend a daily multi-vitamin, especially if the children: Have self-restricted diets Follow a specific diet (for example, if a child is consuming a diet free of casein, a multi-vitamin may be necessary to ensure adequate vitamin D and calcium intake.) Have chronic diarrhea, constipation, or gastrointestinal inflammation The use of mega-dose vitamins and nutritional supplements beyond a multi-vitamin are not fully supported for routine use

Each of these creates a different problem

McNeill, S

Bernini et al

Clinical features reflect the effects of slowed organ function and decreased metabolic rate

Error rates rise due to physiological factors (e.g., residual mouth alcohol, breathing patterns), environmental interference (e.g., acetone in diabetics), or improper calibration