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Both priming and repriming are tested under the same SAC conditions (dose collection apparatus, HPLC assay), and the number of actuations required to achieve label-claim dose output is established for the product labeling
Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate, however, it is imperative to avoid repeated freeze/thaw cycles to maintain peptide integrity
Although these studies have benefited greatly from our extensive knowledge of the pathophysiology of PD [291], a clear therapeutic principle has not yet emerged, complicating the search for more effective therapy targets or treatment strategies for PD (including on demand, biomarker-based therapy) or other movement disorders
